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DeCS
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Descriptor English:
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Farnesyl-Diphosphate Farnesyltransferase
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Descriptor Spanish:
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Farnesil Difosfato Farnesil Transferasa
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Descriptor Portuguese:
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Farnesil-Difosfato Farnesiltransferase
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Synonyms English:
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Squalene Synthetase
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Tree Number:
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D08.811.913.225.431
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Definition English:
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The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl pyrophosphate via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of isoprene intermediates through the sterol pathway. |
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History Note English:
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2006(1975)
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Allowable Qualifiers English:
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Record Number:
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13571
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Unique Identifier:
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D013186
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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